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Ask your health care provider if triamterene may interact with other medicines that you take.

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OtherElevated liver enzymes have been reported in patients receiving MAXZIDE.

Use triamterene during pregnancy with caution if benefits outweigh risks Animal studies show risk and human studies are not availableor neither animal nor human studies were done Discontinue triamterene or breastfeeding.

Triamterene is rapidly absorbed following oral administrationPeak plasma levels are achieved within one hour after dosingTriamterene is primarily metabolized to the sulfate conjugate of hydroxytriamtereneBoth the plasma and urine levels of this metabolite greatly exceed triamterene levels.

Dispense in a tightlight-resistant container as defined in the USP using a child-resistant closure.

Any chloride deficit during thiazide therapy is generally mild and usually does not require any specific treatment except under extraordinary circumstancesas in liver disease or renal diseaseDilutional hyponatremia may occur in edematous patients in hot weatherappropriate therapy is water restrictionrather than administration of saltexcept in rare instances when the hyponatremia is life threateningIn actual salt depletionappropriate replacement is the therapy of choice.

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