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Acetaminophen; chlorpheniramine; dextromethorphan; phenylephrine minor plasma concentrations of dextromethorphan may be elevated when administered concurrently with ciprofloxacin.

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Ciprofloxacin administered together with theophyllineRespbidSlo-BidTheo-24Theolaircan lead to elevatedtoxic blood levels of theophyllineTheophylline is used to open airways in the treatment of asthmaToxic levels of theophylline can lead to seizuresand disturbances in heart rhythmIf concurrent use of ciprofloxacin and theophylline cannot be avoidedfrequent blood tests to monitor theophylline blood levels are recommendedCiprofloxacin increases the effect of tizanidineZanaflexthat is used to treat muscle spasticityThereforethe two drugs should not be combinedIron saltsfor exampleferrous sulfatemay reduce the absorption of ciprofloxacin because of formation of a ciprofloxacin-iron complex that is not absorbableAntacids also may reduce the absorption of ciprofloxacinIf patients are receiving iron salts or antacids and ciprofloxacinthe ciprofloxacin should be given two hours before or six hours after the iron salt or antacidCiprofloxacin may increase the blood thinning effect of warfarinCoumadinJantovenThe reason for this is unknownAnticoagulant activity should be monitored after starting or stopping ciprofloxacinSevelamerRenagelmay reduce the absorption of ciprofloxacin and possibly reduce the effectiveness of ciprofloxacinMilk and orange juice also may reduce the absorption of ciprofloxacinCiprofloxacinas with iron and antacidsshould be given two hours before or six hours after milk or orange juiceAdministration of ciprofloxacin with diabetic medicationsfor example glyburideMicronaseDiabetaGlynasePrestabmay lead to severe low blood glucoseCiprofloxacin may increase blood concentrations of sildenafilViagrathat is used for treating erectile dysfunctionThis combination should be avoided if possiblePatients taking CiproCipro XR can develop sensitivity of the skin to direct sunlightphotosensitivityand should avoid exposure to sunlight or use sunblockFluoroquinolones worsen low blood glucose levels when combined with sulfonylureasfor exampleglyburideMicronaseDiabetaGlynasePrestab

Dry powder for inhalationOrphan designation for patients with NCFB who suffer from frequent severe acute pulmonary bacterial exacerbations which lead to further inflammationairwayand lung parenchyma damage.

Ciprofloxacingeneric nameCiproCipro XRbrand namesis an antibiotic prescribed for the treatment of many skinlungairwayboneand joint infections caused by susceptible bacteriaExamples include complicated urinary tract infectionsUTIsgonorrheachronic bacterial prostatitistyphoid feverchronic bronchitisinfectious diarrhea caused by EcoliShigellaand Campylobacter jejunia nthrax poisoningand TBtuberculosis

Ciprofloxacin administered together with theophyllineRespbidSlo-BidTheo-24Theolaircan lead to elevatedtoxic blood levels of theophyllineTheophylline is used to open airways in the treatment of asthmaToxic levels of theophylline can lead to seizuresand disturbances in heart rhythmIf concurrent use of ciprofloxacin and theophylline cannot be avoidedfrequent blood tests to monitor theophylline blood levels are recommendedCiprofloxacin increases the effect of tizanidineZanaflexthat is used to treat muscle spasticityThereforethe two drugs should not be combinedIron saltsfor exampleferrous sulfatemay reduce the absorption of ciprofloxacin because of formation of a ciprofloxacin-iron complex that is not absorbableAntacids also may reduce the absorption of ciprofloxacinIf patients are receiving iron salts or antacids and ciprofloxacinthe ciprofloxacin should be given two hours before or six hours after the iron salt or antacidCiprofloxacin may increase the blood thinning effect of warfarinCoumadinJantovenThe reason for this is unknownAnticoagulant activity should be monitored after starting or stopping ciprofloxacinSevelamerRenagelmay reduce the absorption of ciprofloxacin and possibly reduce the effectiveness of ciprofloxacinMilk and orange juice also may reduce the absorption of ciprofloxacinCiprofloxacinas with iron and antacidsshould be given two hours before or six hours after milk or orange juiceAdministration of ciprofloxacin with diabetic medicationsfor example glyburideMicronaseDiabetaGlynasePrestabmay lead to severe low blood glucoseCiprofloxacin may increase blood concentrations of sildenafilViagrathat is used for treating erectile dysfunctionThis combination should be avoided if possiblePatients taking CiproCipro XR can develop sensitivity of the skin to direct sunlightphotosensitivityand should avoid exposure to sunlight or use sunblockFluoroquinolones worsen low blood glucose levels when combined with sulfonylureasfor exampleglyburideMicronaseDiabetaGlynasePrestab

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