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Figure 2 Kaplan-Meier Estimates of Overall SurvivalAll Randomized Population)

In the UKlive vaccines include rubellamumpsmeaslesBCGyellow fever and shingles vaccineZostavax

Severe mucocutaneous reactionssome with fatal outcomesuch as Stevens-Johnson syndrome and Toxic Epidermal NecrolysisTENcan occur in patients treated with XELODAsee ADVERSE REACTIONSXELODA should be permanently discontinued in patients who experience a severe mucocutaneous reaction possibly attributable to XELODA treatment.

Dehydration has been observed and may cause acute renal failure which can be fatalPatients with preexisting compromised renal function or who are receiving concomitant XELODA with known nephrotoxic agents are at higher riskPatients with anorexiaasthenianauseavomiting or diarrhea may rapidly become dehydratedMonitor patients when XELODA is administered to prevent and correct dehydration at the onsetIf grade 2or higherdehydration occursXELODA treatment should be immediately interrupted and the dehydration correctedTreatment should not be restarted until the patient is rehydrated and any precipitating causes have been corrected or controlledDose modifications should be applied for the precipitating adverse event as necessarysee DOSAGE AND ADMINISTRATION

Capecitabine is a chemotherapy drug and is also known by its brand name Xeloda.

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